Sep 6, 2007: Sequencing: The next generation
Filed in: Colloquium
Scott Emrich, University of
Notre Dame
Substantial reductions in the cost of large-scale genome sequencing have required significant advances in computing. In this seminar, I will describe Next-gen sequencing platforms such as the ABI SOLiD, Illumina’s Solexa technology and 454 Life Sciences’ FLX, their applications, and corresponding open computational problems. Solving the grand challenge in this fieldaffordable and highly efficient sequencing of a human genomewill earn a $10mil X-prize.
Current research opportunities in computational plant genomics will also be presented, with an emphasis on our corn genome project and its relationship to other cereal crops and proposed biorenewable sources of energy (e.g., switchgrass).
Abstract
Substantial reductions in the cost of large-scale genome sequencing have required significant advances in computing. In this seminar, I will describe Next-gen sequencing platforms such as the ABI SOLiD, Illumina’s Solexa technology and 454 Life Sciences’ FLX, their applications, and corresponding open computational problems. Solving the grand challenge in this fieldaffordable and highly efficient sequencing of a human genomewill earn a $10mil X-prize.
Current research opportunities in computational plant genomics will also be presented, with an emphasis on our corn genome project and its relationship to other cereal crops and proposed biorenewable sources of energy (e.g., switchgrass).